Multiple synergizing factors contribute to the strength of the CD8+ T cell response against listeriolysin O

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Multiple synergizing factors contribute to the strength of the CD8+ T cell response against listeriolysin O.

Immunodominance in CD8+ T cell responses against Listeria monocytogenes is a well-recognized but still not fully understood phenomenon. From listeriolysin, the major virulence factor of L. monocytogenes, only a single epitope, pLLO91-99, is presented by MHC class I molecules in BALB/c mice which dominates the cytotoxic T cell response against this bacterial pathogen. To obtain more insights int...

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ژورنال

عنوان ژورنال: International Immunology

سال: 2005

ISSN: 1460-2377,0953-8178

DOI: 10.1093/intimm/dxh352